Tequila, orange liqueur, and lime juice. Nothing quite beats the perfectly balanced salty, sour, sweet, and sharp flavors of a classic margarita. Drink it on the rocks, frozen, or as a fantastically unique recipe featuring exotic ingredients.

If you’re looking to taste the best margaritas New Mexico has to offer, you’ll want to check out the official Margarita Trail in Santa Fe. This trail features a whopping 45 margaritas. That might be a bit much to attempt to tackle in a weekend so we’ll start by introducing you to just five.

  1. Smoked Sage Margarita at Secreto Lounge

Hotel St. Francis/Google

Erik Ellis/Google This award-winning restaurant shows off a long list of signature cocktails, each featuring garden-fresh ingredients. The margarita specialty here is an intriguing smoked sage margarita served on the rocks with a salted, smokey rim. Address: 210 Don Gaspar Ave., Santa Fe, NM 87501 Phone: (505) 983-5700 Website: Hotel St. Francis

  1. Meowgarita at Float Cafe & Bar

Ibrown/TripAdvisor

Carter Sutton/Google Looking for an exceptionally unique take on the classic margarita? It doesn’t get much more colorful and playful than the cocktail at Meow Wolf’s own bar. It incorporates a butterfly pea flower tea and cotton candy. Address: 1352 Rufina Cir., Santa Fe, NM 87507 Phone: (505) 395-6369 Website: Meow Wolf

  1. Amaya Jalapeño Margarita at Amaya

Lars Ulrik Wacher Hansen/Google

Hotel Santa Fe/Facebook Located inside the Hotel Santa Fe, this luxurious restaurant serves some spectacular meals and you’ll definitely want to pair any of those with this spicy margarita. Address: 1501 Paseo de Peralta, Santa Fe, NM 87501 Phone: (505) 955-7805 Website: Hotel Santa Fe

  1. Peso de Plata Margarita at Blue Corn Cafe

Josiah B/TripAdvisor

Blue Corn Cafe/Facebook If a traditional-style margarita is what best piques your palate, you’ll want to try this silver coin marg which comes with Jose Cuervo Silver, Cointreau, and fresh lime juice. It’s the perfect accompaniment to tacos. Address: 133 Water St., Santa Fe, NM 87501 Phone: (505) 984-1800 Website: Blue Corn Cafe

  1. Sandia & Pepino Margarita at Anasazi Restaurant & Bar

Rosewood Inn of the Anasazi/Facebook

Anasazi Restaurant/TripAdvisor Located inside the Rosewood Inn of the Anasazi, the restaurant and bar here is home to one wonderfully fruity margarita. Flavored with watermelon and cucumber juices, you’ll also get a nice kick to your drink since the rim is lined with a Tajin, a lime, and chili-infused salt. Address: 113 Washington Ave., Santa Fe, NM 87501 Phone: (505) 988-3236 Website: Rosewood Inn of the Anasazi

You can find all 45 margaritas and their restaurants by visiting Santa Fe’s tourism website.

Hotel St. Francis/Google

Erik Ellis/Google

This award-winning restaurant shows off a long list of signature cocktails, each featuring garden-fresh ingredients. The margarita specialty here is an intriguing smoked sage margarita served on the rocks with a salted, smokey rim. Address: 210 Don Gaspar Ave., Santa Fe, NM 87501 Phone: (505) 983-5700 Website: Hotel St. Francis

Ibrown/TripAdvisor

Carter Sutton/Google

Looking for an exceptionally unique take on the classic margarita? It doesn’t get much more colorful and playful than the cocktail at Meow Wolf’s own bar. It incorporates a butterfly pea flower tea and cotton candy. Address: 1352 Rufina Cir., Santa Fe, NM 87507 Phone: (505) 395-6369 Website: Meow Wolf

Lars Ulrik Wacher Hansen/Google

Hotel Santa Fe/Facebook

Located inside the Hotel Santa Fe, this luxurious restaurant serves some spectacular meals and you’ll definitely want to pair any of those with this spicy margarita. Address: 1501 Paseo de Peralta, Santa Fe, NM 87501 Phone: (505) 955-7805 Website: Hotel Santa Fe

Josiah B/TripAdvisor

Blue Corn Cafe/Facebook

If a traditional-style margarita is what best piques your palate, you’ll want to try this silver coin marg which comes with Jose Cuervo Silver, Cointreau, and fresh lime juice. It’s the perfect accompaniment to tacos. Address: 133 Water St., Santa Fe, NM 87501 Phone: (505) 984-1800 Website: Blue Corn Cafe

Rosewood Inn of the Anasazi/Facebook

Anasazi Restaurant/TripAdvisor

Located inside the Rosewood Inn of the Anasazi, the restaurant and bar here is home to one wonderfully fruity margarita. Flavored with watermelon and cucumber juices, you’ll also get a nice kick to your drink since the rim is lined with a Tajin, a lime, and chili-infused salt. Address: 113 Washington Ave., Santa Fe, NM 87501 Phone: (505) 988-3236 Website: Rosewood Inn of the Anasazi

Margaritas are wonderfully delicious but not for everyone. If you prefer the malty, hoppy flavors of beer, then we bet you will absolutely love checking out our state’s own ale trail in Las Cruces. Read more about this unique trail in Not Many People Know New Mexico Has An Ale Trail And It Is Positively Intoxicating.

OnlyInYourState may earn compensation through affiliate links in this article.

Address: 210 Don Gaspar Ave, Santa Fe, NM 87501, USAAddress: 1352 Rufina Cir, Santa Fe, NM 87507, USAAddress: 1501 Paseo De Peralta, Santa Fe, NM 87501, USAAddress: 133 W Water St, Santa Fe, NM 87501, USAAddress: 113 Washington Ave, Santa Fe, NM 87501, USA